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Future Clayton Laboratory Projects:

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Publications

Clayton, S. W., Walk, R. E., Mpofu, L., Easson, G. W., & Tang, S. Y. (2024). Analysis of Infiltrating Immune Cells Following Intervertebral Disc Injury Reveals Recruitment of Gamma-Delta (γδ) T cells in Female Mice. 
https://www.biorxiv.org/content/10.1101/2024.03.01.582950v1 (in revision at OAC)

Clayton, S. W., Sebastian, A., Wilson, S. P., Hum, N. R., Walk, R. E., Easson, G. W. D., Vaidya, R., Broz, K. S., Loots, G. G., & Tang, S. Y. (2024). Single cell RNA sequencing reveals a shift in cell function and maturation of endogenous and infiltrating cell types in response to acute intervertebral disc injury. bioRxiv, 2024.2008.2010.607363. https://doi.org/10.1101/2024.08.10.607363 (in review at JBMR plus)

Gonzalez, C. E., Vaidya, R. S., Clayton, S. W., & Tang, S. Y. (2024). Secreted chemokines reveal diverse inflammatory and degenerative processes in the intervertebral disc of the STZ-HFD mouse model of Type 2 diabetes. bioRxiv, 2024.2007.2031.605332.https://doi.org/10.1101/2024.07.31.605332

Buettmann, E. G., Chlebek, C., Lockard, C. A., Clayton, S. W., Lewis, K. J., & Collins, K. H. (2023). Post or perish? Social media strategies for disseminating orthopedic research. J Orthop Res, 41(8), 1643-1652.  
https://onlinelibrary.wiley.com/doi/10.1002/jor.25588

Rohanifar, M., Clayton, S. W., Easson, G., Patil, D. S., Lee, F., Jing, L., Barcellona, M. N., Speer, J. E., Stivers, J. J., Tang, S. Y. & Setton, L. A (2022).  “Single Cell RNA-Sequence Analyses Reveal Uniquely Expressed Genes and Heterogeneous Immune Cell Involvement in the Rat Model of Intervertebral Disc Degeneration.” Applied Sciences, 12, 8244.
https://www.mdpi.com/2076-3417/12/16/8244

Clayton, S. W., A. Angermeier, J. E. Halbrooks, R. McCardell and R. Serra (2022). "TGFβ signaling is required for sclerotome resegmentation during development of the spinal column in Gallus gallus." Developmental Biology. 488: 120-130.
https://www.sciencedirect.com/science/article/pii/S0012160622001014?via%3Dihub

Clayton, S. W., Ban, G. I., Liu, C., & Serra, R (2020). “Canonical and noncanonical TGF-β signaling regulate fibrous tissue differentiation in the axial skeleton.” Scientific reports. 10(1), 21364.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7721728/

Ban, Ga I., Williams, S., R. Serra., (2019). "Antagonism of BMP signaling is insufficient to induce fibrous differentiation in primary sclerotome." Exp Cell Res 378(1): 11-20.
https://pubmed.ncbi.nlm.nih.gov/30817928/

Williams, S., B. Alkhatib and R. Serra (2019). “Development of the axial skeleton and intervertebral disc.” Current Topics in Developmental Biology: Vertebrate Skeletal Development. Elsevier (133) 49-90
https://pubmed.ncbi.nlm.nih.gov/30902259/

Alkhatib, B., G. I. Ban, S. Williams and R. Serra (2018). "IVD Development: Nucleus Pulposus Development and Sclerotome Specification." Current Molecular Biology Reports: 1-10.
https://pubmed.ncbi.nlm.nih.gov/30505649/

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